glp-1 gip therapies weight management effectiveness Obesity Clinical Trials Frontiers | GLP−1 receptor agonists

By week 30, only 28% of people on placebo had an HbA1c (the average blood sugar levels over the last three months) less than 7%, whereas as much as 70% or more of people on any dose of Ozempic achieved an A1C of less than 7%

Nature Medicine, 28(11), 22222233

A patient who begins GLP-1 therapy often experiences significant fatigue, nausea, and reduced appetite in the early weeks

Plasma glucose is lowered by effects on insulin and glucagon secretion, and by decelerating gastric emptying

Article Summary GLP-1 medications such as Semaglutide and Tirzepatide can be highly effective for adults struggling with metabolic weight gain, appetite dysregulation, and insulin resistance but they are not right for everyone

H., Lingvay, I., Deanfield, J., et al