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Central GLP-1 receptor activation improves cholesterol metabolism partially independent of its effect on food intake

Furthermore, the activation of GLP-1R signaling in the ventromedial hypothalamus (VMH) can also control energy expenditure by promoting food intake-independent weight loss by inducing brown adipose tissue (BAT) thermogenesis and browning through a sympathetic drive to BAT [6]

doi: 10.1016/j.bcp.2013.12.012 69 HaanMN

In other cases, you select the amount of medication to be injected

Last but not least, inflammation modulation also contributes to vascular protection