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To date, almost all high-quality pediatric clinical trials have been relatively brief (typically 12 years) (34, 36), so the long-term efficacy and safety of GLP-1 RAs in youth are unknown
In a Phase III trial targeting people with obesity but not diabetes, Novo aimed for 25% weight loss a goal it missed in December
(NIDDK) Part of the effect also happens in the gastrointestinal tract
The evidence supports two general conclusions: 1) approximately one quarter of weight loss will be FFM 2) SMM accounts for approximately 50% of FFM (see Table 1 below)
healthcare system is at a turning point as the dual epidemics of obesity and type 2 diabetes drive demand for advanced treatments
