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Victoza was initially approved for treating type 2 diabetes until its weight loss effects were noticed

Collectively, these sources indicate GLP-1 PA denials are typically in the 6080% range on first pass (dramatically higher than the ~11% average across all drugs)

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The PlexusDx Precision Peptide Genetic Test examines 14 metabolic pathways across 49 peptide-related genes, including variants in GLP1R (rs6923761) and GIPR (rs1800437) that predict lipid response patterns