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Mitigating Side Effects Several strategies have proven effective for managing adverse events: Starting with lower doses (e.g., 0.5 mg) rather than higher doses Implementing gradual dose escalation with adequate time between increases Maintaining patients at current doses longer when side effects emerge Monitoring and providing supportive care for gastrointestinal symptoms[8] These approaches can significantly improve tolerability and adherence to the medication regimen

Glucagon-like peptide-1 (GLP-1) is an incretin peptide hormone mainly secreted by enteroendocrine intestinal L-cells

Although long-term safety and efficacy require further evaluation, current evidence positions GLP-1 RAs as promising therapeutic agents in translational geroscience, with the potential to mitigate age-related physiological decline and promote a longer, healthier lifespan.

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Incretinas