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10.1016/j.jacc.2024.11.001 [DOI] [PubMed] 87.Sattar N, McGuire DK, Pavo I, et al

GLP-1 receptor agonists and GLP-1 and glucose-dependent insulinotropic peptide agonists have several mechanisms of action, including reduction of gastric emptying, inhibition of glucagon secretion, beneficial changes in the intestinal microbiome, and direct effects on hypothalamic nuclei to enhance satiety (which promotes weight loss)

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GLP-1R was only present in cells, a finding similar to some reports, 45, 46 however, different from others, which reported the GLP-1R also in cells

Some patients appreciate daily dosing because it allows more responsive dose adjustments and produces a predictable routine

The FDA reported that Blaine Labs is recalling certain wound care gels due to contamination with Lysinibacillus fusiformis, a bacteria that may cause infections