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Science has advanced

Contact your GP if sulphur burps persist beyond 8-12 weeks, worsen over time, or are accompanied by severe abdominal pain, persistent vomiting, or inability to keep fluids down
Older anti-obesity medications were also not as effective and had important safety concerns

Semaglutide could ultimately be a valuable pharmacological alternative or add-on to these medications, however, more studies are needed to determine the efficacy of this drug, as well as its safety in people with average and below average BMI for whom weight loss could cause medical problems

Gastric distension-induced c-fos expression in catecholaminergic neurons of rat dorsal vagal complex

Within 5-10 years, the GLP-1 therapy landscape will likely include multiple oral options at various price points, fundamentally changing how metabolic disease is managed in primary care
