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In scientific reports and clinical trials, a titration model was used to assess tolerance, safety and metabolic response as the concentration of the active substance was increased
Invest Ophthalmol Vis Sci 55(12):81739 Thaller M et al (2023) The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is highly expressed in mouse tissues with metabolic function
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But theyre being prescribed for obesity both on- and off-label, depending on the drug in question
