oral glp-1 weight loss US FDA accepts Novo Nordisk's application for Wegovy for Oral GLP-1

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Mood symptoms Animal studies, case reports, and a meta-analysis of RCTs of GLP-1 RAs suggest that these medications might help with depression (Chen X et al, Am J Geriatr Psychiatry 2024;32(1):117127)

Broader Cancer Outcomes and Mechanistic Insights For most other cancers, recent clinical evidence demonstrates largely positive outcomes, with several meta-analyses showing no excess risk and even a reduced risk for hepatocellular carcinoma and colorectal cancer (relative to insulin users)

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doi: 10.3389/fphar.2021.672515

When caloric intake drops significantly, the resulting energy deficit can manifest as fatigue, weakness, or reduced exercise tolerance