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However, in rare cases, more severe side effects may occur, such as pancreatitis, gallbladder issues, renal dysfunction, and even a potential risk of thyroid tumors

Gastrointestinal side effects tend to be worst early on or after a dose increase and frequently ease as your body adjusts over several weeks

Specifically, a higher proportion of cholelithiasis events was seen for semaglutide (1.4%) versus placebo (1.1%) in the SELECT study

Telogen effluvium, the likely underlying cause, is generally self-limiting and affects a proportion of individuals undergoing rapid weight reduction, regardless of the method (whether pharmacological, surgical, or dietary)

Moreover, studies highlight its potential cardiovascular benefits

Glucagon receptor activation ramps up how many calories your body burns at rest true thermogenesis, not just eating less