glp 1 agonist and alcohol use disorder Repurposing GLP-1 receptor agonists for disorder: a systematic review meta-analysis | Diabetology & Metabolic Syndrome Effects of GLP‐1 Receptor Agonists

2022;1(6) doi: 10.1056/evidoa2200014

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Taken together, the ISR and cAMP findings support the hypothesis that GLP-1R-mediated increases in cAMP potentiate insulin secretion, but that simultaneous occupation of Y1-R prevents binding to GLP-1R and/or the capacity to elicit relevant downstream responses

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