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cite Evidence and approval: Several injectables are FDA-approved specifically for chronic weight management after large trials

Regulatory guidance from UK and European authorities advises caution in patients with a history of pancreatitis

If recovery is adequate, volume can increase toward 16 to 20 weekly sets during the intensification phase

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MAESTRO-NASH safety profile [3] Other NASH Therapies in Clinical Trials The pathways leading to NASH are complex, primarily originating from targets such as carbohydrate and lipid metabolism, lipid toxicity and cell death, inflammation, and anti-fibrosis targets associated with extracellular matrix deposition (Figure 5)