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In spite of the substantially reduced coupling to G s , exendinphe1 acts as a full agonist for acute cAMP production in pancreatic beta cells as well as heterologous cell lines (Jones, Bloom, et al., 2018), presumably due to the availability of spare receptors and signal amplification
doi:10.1074/jbc.M109.033829
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Shifts in estrogen and progesterone can change where you store fat, how you sleep, how you crave, and how you recover
