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Description
The LES is a muscular valve that normally keeps stomach contents where they belong

Cemal, Ozemak: Wolters Kluwer

Its legacy extends into domains such as metabolic fitness, physique, and psychology
Specific GLP-1 receptor agonists (liraglutide, semaglutide, dulaglutide) have demonstrated cardiovascular benefits in clinical trials, including reduced risk of major adverse cardiovascular events

This gives the food time to begin digestion before the GLP-1-mediated gastric slowing kicks in

Any such program must be vetted with legal and regulatory guidance
