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This is over $540 billion a year if all eligible individuals used itaround 12% of total US healthcare expenditure
Longer-term concerns include a potential increased risk of pancreatitis, bowel obstruction, and thyroid cancer

At an event hosted by Stat News, Richard Pazdur, former director of the FDAs Center for Drug Evaluation and Research, told attendees that biopharmaceutical industry leaders were not concerned enough about the state of the FDA

Long-term maintenance and continued progress are also possible with ongoing therapy, healthy nutrition, and regular physical activity
cid=53375 (22 December 2025, data last accessed)

doi: 10.1016/j.cell.2019.05.004 [DOI] [PMC free article] [PubMed] [Google Scholar] 152
