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Compounded semaglutide is often made using either: Semaglutide base (chemically identical to branded versions) Semaglutide sodium salt (a newer form, but with less data behind it) Important Note: Compounding pharmacies must source semaglutide from FDA-registered facilities that follow strict USP standards or use FDA approved products (Rybelsus) in alternative dosage forms or strengths

In 2021, semaglutide under the name Wegovy was approved for weight loss

Freezing temperatures damage the molecular structure of the peptide and render it ineffective, so never place semaglutide in the freezer, even briefly during transport

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Novo Nordisk will take legal and regulatory action to protect patients, our intellectual property and the integrity of the US gold-standard drug approval framework." Hims & Hers started selling a compounded version of injectable semaglutide in 2024, while the drug was still deemed to be in short supply

You would need life-threatening complications from your weight, like severe heart failure or the inability to breathe properly