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In a retrospective analysis of more than 60,000 patients aged 40 years and older, researchers found that individuals initiating treatment with GLP-1 receptor agonists had better long-term neurological and survival outcomes than those taking other classes of antidiabetic drugs

2008, Noyan-Ashraf et al

For all-cause mortality and RFS in patients with obesity, the 5-year survival probability was 97.4% and 96% with GLP-1 RA use, and 93.2% and 91.3% with non-use, respectively

Pharmacological profile of lixisenatide: A new GLP-1 receptor agonist for the treatment of type 2 diabetes

The first GLP-1RA, exenatide, was synthesized to mimic hormones discovered in Gila monster saliva and was approved by the Food and Drug Administration (FDA) in 2005, launching a new era in diabetes pharmacotherapy.[4, 22] In the two decades since exenatides approval, a number of additional GLP-1RAs have joined the class

Editors Note: The immune system is a viciously complex topic