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Anini Y, Fu-Cheng X, Cuber JC, Kervran A, Chariot J, Roz C
doi: 10.1056/NEJMoa0806375
Efficacy of Weight-loss A recent systematic review and a meta-analysis by Wong et al (2025) found that GLP-1 receptor agonists induced an additional 4.45 kilogram of weight loss over placebo based on 47 randomized control trials with a cohort of 23,244 patients

A Scientific Statement from the Heart Failure Society of America advised patients with a BMI of 35 kg/m2 or higher to aim for a weight reduction of 5 to 10%

Medical management of hyperglycaemia in type 2 diabetes mellitus: A consensus algorithm for the initiation and adjustment of therapy: A consensus statement from the American Diabetes Association and the European Association for the Study of Diabetes
