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Higher predisposition to adverse effects Additionally, people who had previously used gastrointestinal medications -- which may indicate they are more vulnerable to the common adverse gastrointestinal side-effects reported by GLP1-RA users, such as nausea, vomiting, diarrhea -- were 9% more likely to discontinue semaglutide within the first year

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It suppresses appetite and promotes fat burning, significantly Lanreotide Acetate Lanreotide acetate is a long-acting somatostatin analog for acromegaly and GEP-NETs, providing sustained release after injection

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The GRADE evaluation of the evidence retrieved for the primary endpoint (MASH remission, Supplementary Table 3) was rated as high and low for tirzepatide and semaglutide, respectively (Supplementary Table 6)