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The primary retatrutide literature includes a discovery and preclinical characterization paper in Cell Metabolism (2022), a cryo-electron microscopy structural study in Cell Discovery (2024), a phase 1b multiple-ascending-dose trial in The Lancet (2022), and phase 2 trials reported in the New England Journal of Medicine (2023), The Lancet (2023), and Nature Medicine (2024)

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Alcohol use may increase the risk of hypoglycemia

Adverse Event Reporting Severe Reactions If you experience any severe or life-threatening symptoms, discontinue use and seek emergency medical care
