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633 NAD + is synthesized from both de novo pathway and the salvage pathway

furthermore, the risk increases with longer treatment durations, higher doses, and when these agents are used for weight loss

A comprehensive literature search across multiple databases identified a total of 6,541 studies, retrieved from PubMed ( n = 848), Web of Science ( n = 1,015), Scopus ( n = 2,523), Embase ( n = 1,525), Cochrane ( n = 367), as well as Google Scholar and manual reference searches ( n = 263)

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