semaglutide and smoking may help quit smoking, shows new study that calls for clinical trials Smoking While Taking Semaglutide: Safety

K., Abokhrais, I

A stall at week 8 requires different interventions than a slowdown at week 30

However, important considerations include: Oral semaglutide (Rybelsus): The SmPC for Rybelsus specifically states it must be taken on an empty stomach with water only, followed by at least 30 minutes before any food, drink or other oral medicines (including magnesium supplements)

An H, et al

In contrast, two studies, including 41,046 exposed pregnancies and 131,407 comparator pregnancies, identified a statistically significant association with urinary congenital malformations (OR 1.24

However, it is hypothesized that the drug may work by decreasing appetite, slowing down gastric emptying, and potentially influencing the brains reward system