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It enhances glucose-dependent insulin secretion, suppresses glucagon, and slows gastric emptying key mechanisms for glucose control

Major drugmakers are investing in technologies to make GLP-1 pills more effective

But some see much less benefit, and researchers are trying to figure out why.

Patients with type 2 diabetes who are prescribed liraglutide have a 179% higher likelihood of developing non-arteritic anterior ischemic optic neuropathy (NAION), while those prescribed insulin have an 86% greater likelihood compared to patients who were prescribed other diabetes medications

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Understanding the difference between appetite-suppressing drug classes helps patients and providers choose the most appropriate treatment based on individual physiology, comorbidities, and clinical response patterns
