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T., Botros, F

The Bottom Line The strongest candidates for retatrutide are adults with a BMI of 30 or higher, or 27 or higher with a metabolic comorbidity, who have not achieved adequate results through lifestyle changes or existing medications

How to use Ozempic pens Like other GLP-1 drugs (Wegovy), Ozempic is a weekly injection used for reducing blood sugar levels and also used off-label to reduce body weight

Abbreviations ASCVD: Atherosclerotic cardiovascular disease BMI: Body mass index CI: Confidence interval CKD: Chronic kidney disease CVD: Cardiovascular disease eGFR: Estimated glomerular filtration ratio GLP-1RA: Glucagon-like peptide-1 receptor agonist HFpEF: Heart failure with preserved ejection fraction HFrEF: Heart failure with reduced ejection fraction HHF: Heart failure hospitalization HR: Hazard ratio LDL: Low-density lipoprotein LVEF: Left ventricular ejection fraction MACE: Major cardiovascular events MRA: Mineralocorticoid receptor antagonist SGLT2: Sodium-glucose cotransporter 2 References Wong ND, Sattar N

What Should GLP-1 Users Track to Protect Lean Muscle

Authorities are monitoring how these drugs are being used across different care settings, including telehealth platforms and direct-to-consumer models