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Among regular drinkers, consumption plummeted from 23.2 to 7.8 units per week a 68 percent reduction, which Professor le Roux noted is comparable to that achieved by nalmefene, a drug used to treat alcohol use disorder in Europe. The potential for these weight loss drugs to reduce alcohol consumption could yield additional public health and economic benefits

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And for the last two years, one drug class has quietly started eating the entire wellness market alive - GLP-1

Berberine is not a GLP-1 agonist, though both compounds influence metabolic pathways