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Nat Med 31 , 544551 (2025)

Recommended for individuals with a BMI of 30 or higher, or 27 with a weight-related condition, Wegovy demonstrated an average weight loss of 15% over 68 weeks in trials

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Frequently asked questions (FAQs) What is better for weight loss, Ozempic or Mounjaro

Following a year of treatment with Mounjaro (tirzepatide), weight loss is around 20% or more, and diabetes symptoms can also be effectively controlled

Studies examining patients on antidepressants who started GLP-1 receptor agonists found that those on bupropion specifically tended to fare better in terms of weight loss compared to those on SSRIs like sertraline or fluoxetine