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Efficacy and safety of liraglutide versus placebo added to basal insulin analogues (with or without metformin) in patients with type 2 diabetes: A randomized, placebocontrolled trial

Infusion of GLP-1 into healthy humans and diabetics by several groups established the role of GLP-1 as an incretin and a potential therapeutic for diabetes

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ArticlePubMed 171

What researchers study it for: GLP-1 receptor pharmacology how the receptor is activated and signals Blood-sugar and metabolic models a core area of study Comparative research a benchmark against dual/triple agonists Appetite-signaling pathways how the GLP-1 system is wired A benchmark molecule is only useful if it is exactly what the label claims that is the whole point of a reference compound