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Rapid weight loss can disrupt oestrogen levels and the hypothalamic-pituitary-ovarian axis, potentially causing irregular periods or temporary amenorrhoea

However, many people find that their body adapts more quickly to each subsequent dose increase because the underlying mechanisms (caloric deficit, metabolic adaptation) are already partially adjusted

Severe Gastrointestinal Adverse Reactions Inform patients of the potential risk of severe gastrointestinal adverse reactions

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