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Weve all heard that stopping taking a GLP-1 medication for weight losssuch as semaglutide (marketed as Wegovy) and tirzepatide (sold as Zepbound)often leads to rapid weight gain, with people returning to baseline in as little as 18 months

It was one of the American College of Cardiology's top five trends in 2025.

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Weight gain after stopping Ozempic and other GLP-1 medications is quite common

Patients should be alert for: Allergic reaction: Rash, itching, swelling (especially of face/tongue/throat), dizziness, or trouble breathing