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[DOI] [PubMed] [Google Scholar] 26.Larussa T., Oliverio M., Suraci E., Greco M., Placida R., Gervasi S., Marasco R., Imeneo M., Paolino D., Tucci L., et al

Obesity and metabolic disorders are closely associated with systemic inflammation

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Mechanistically, multi-omics analyses of cardiac and hepatic tissues revealed that semaglutide exerted these benefits by improving cardiac metabolism, interfering with pro-fibrotic and pro-hypertrophic signals, and by reducing systemic inflammation

Stopping any effective weight loss tool without a maintenance plan produces the same rebound, which is why the taper, the habits, and the follow-up matter more than the specific drug