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Link Henshaw D, Sparler N, Talbott A, et al

GLP-1 induced activation of PKA increases Pdx1 expression and translocation of Pdx1 to the nucleus, where Pdx1 binds to the insulin promoter to initiate insulin expression and synthesis (Figure 5) [490,524]

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doi: 10.1177/2042018821997320 [DOI] [PMC free article] [PubMed] [Google Scholar] 35
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Some of them even hit $800k+/month in their first few months
