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Current evidence supports the safety profile of GLP-1 medications when prescribed appropriately, with benefits in glycaemic control and cardiovascular risk reduction generally outweighing theoretical thyroid concerns for most patients
I've had so many friends and readers ask my opinion on this the last couple of years, so I thought it was important to finally write about it
At the time, prescribers were warned to only use the drugs for their licensed indication and to avoid initiating GLP-1 RAs for T2DM patients during the shortage
Vorzugsweise werden bei einer chronischen Niereninsuffizienz SGLT-2-Inhibitoren empfohlen
In contrast, the longer-acting GLP-1RAs such as liraglutide and semaglutide, engineered for greater resistance to degradation, demonstrate poor penetration into the central nervous system (Salameh et al., 2020)
J Biol Chem., 283, 11340-7
