glp-1 thyroid The Truth About GLP-1s, Meds & Hormone Therapy – Real Answers with McCall McPherson Letter: Association Between Incretin Mimetics

What Clinical Trials Reveal About Tirzepatide and Mood The SURMOUNT-4 trial and other major studies tracking tirzepatide found that depression and anxiety each occurred in fewer than 2% of participants at treatment-ending doses

Lewis says

About 4% of GLP-1 users developed osteoporosis, compared with a little over 3% of nonusers an increased risk of about 30%

The short answer: it depends

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For example, many L-cells in the distal jejunum and ileum coexpress GLP-1 and PYY (14), whereas proximal L-cells can also produce GLP-1 (15), in addition to secreting CCK, GIP, neurotensin, or secretin (16)