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Here are some practical approaches: Gradual Dose Escalation: Starting with a lower dose and gradually increasing can help mitigate side effects

Liraglutide: Once a day

Regular Exercise: Aim for at least 150 minutes of moderate-intensity exercise per week

The Bio Report Podcast: Obesity Therapy Unmet Needs This podcast discusses unmet needs in the obesity space related to lack of tolerability, muscle loss, and weight rebound after therapy discontinuation, and the potential role of peripheral CB1 inhibition to help address these issues

The goal of GLP-1 therapy is not starvation
After 12 weeks at this maintenance dosage, if the patient has not lost at least 5% of body weight, Contrave should be discontinued
