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Glucagon-like peptide-1 (GLP-1) is a hormone involved in regulating blood sugar, appetite, and metabolism

Drugs that have already demonstrated strong properties in decreasing low-grade systemic inflammation could also act locally at the joint level [17]

The role of glucagon in maintaining glucose homeostasis by increasing hepatic gluconeogenesis and glycogenolysis in response to low glucose levels has been exhaustively studied

Plasma adiponectin levels inversely correlate to clinical parameters in type 2 diabetes mellitus patients with macrovascular diseases

10.1016/B978-0-12-417150-3.00009-0

This binding triggers intracellular signaling cascades that result in proglucagon processing and GLP-1 secretion