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First, exclude other causes of musculoskeletal symptoms, including inflammatory arthritis, infection, trauma, or medication interactions

Although the SAVOR and EXAMINE studies were delineated to verify cardiovascular safety of two DPP-4i, namely saxagliptin and alogliptin, respectively, both are considered to be the first controlled clinical trials to address the effect of GLP-1 system on CVD

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Read about the weight loss drugs currently in clinical trials at Eli Lilly and Novo Nordisk here: GLP-1 drugs also include a warning about the risks of thyroid cancer that have been observed in animal studies