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In late-stage type 2 diabetes mellitus (T2DM), impaired islet cell function leads to absolute insulin deficiency, thereby disrupting blood glucose homeostasis

The composite endpoint was achieved by 71.4%, 77.5%, and 31.4% of the population in the semaglutide 0.5 mg, 1.0 mg, and sitagliptin group, respectively

The WHO describes obesity as a chronic disease requiring long-term, structured care.

Most semaglutide side effects resolve within one to four weeks after stopping the medication, though individual timelines vary based on dose duration and metabolic factors

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