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The Indiana-based pharmaceutical company in a press statement said that retatrutide, a once-weekly triple hormone receptor agonist, led to an average weight loss of 70.3lb (28.3%) over 80 weeks among participants receiving the 12mg dose, with 45.3% achieving at least 30% weight loss

Ok #1 as a Naturopathic Doctor that has been around since Herbal Phen Fen, regular Phen Fen, the HCG diet, the HGH diet, Keto Diet, Celery Juice, etc

Most people lose no more than 1 kg in the first week, mainly from water loss and appetite suppression

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If sleep disturbances persist beyond 23 weeks or significantly impair daily functioning, consult your GP or prescribing clinician for advice

[DOI] [PubMed] [Google Scholar] 65.MacDonald PE, El-Kholy W, Riedel MJ, Salapatek AM, Light PE, Wheeler MB