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GLP-1 agonists directly bind to and activate GLP-1 receptors on pancreatic cells, while berberine works primarily through AMPK activation and does not directly interact with GLP-1 receptors
Hydrogen-rich water partially alleviate inflammation, oxidative stress and intestinal flora dysbiosis in DSS-induced chronic ulcerative colitis mice

Dietary fiber from fruits, vegetables, and whole grains are broken down in the gut by bacterial fermentation 10
A deficiency of gastric interstitial cells of Cajal accompanied by decreased expression of neuronal nitric oxide synthase and substance P in patients with type 2 diabetes mellitus
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