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Am J Ophthalmol [Internet]

In studies with multiple treatment arms, including combination therapies and monotherapies with either SGLT-2i, GLP-1RA, or TAU, we restructured these into separate comparisons

Another CRL came two months later, when the FDA rejected the companies bid for the interchangeability designation
Stark J, Klass MJ, Owen L

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For the first part of the question we actually published our second publication was exactly what you're asking
