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Description
Relative P-AKT expression levels were normalized to -actin and expressed as fold change compared to the control group

Post hoc pairwise comparisons between therapy groups were conducted using Tukeys honest significant difference (HSD) test to control for the family-wise error rate associated with multiple comparisons (R code is available in Supplemental Methods)
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The reasoning: when the tablet dissolves on the tongue, some absorption happens through the oral mucosa (buccal absorption)
Semaglutide belongs to a group of medications known as GLP-1 receptor agonists