new indications for glp-1 drugs What to Make of the Coverage and Cost Landscape New Molecules and Emerging Indications
Description
Cost : Tirzepatide is comparably priced to other GLP-1 RAs on the market at $974.33 for four weekly doses, regardless of dose size

Their effects on the individual components of MACE, myocardial infarction (reduced in LEADER and Harmony Outcomes), and stroke (reduced in SUSTAIN-6 and REWIND), varied in each trial (Table 1)

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The clinical and economic implications of indefinite treatment are considerable, driving innovation in approaches that might allow successful maintenance without continuous medication or that could extend dosing intervals substantially

The addition resulted in effective glycemic control (between-treatment difference in least squares mean change from baseline, -0.70%) and the changes were well tolerated, with no increased risk of hypoglycemia compared with the placebo (2 vs
