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GLP-1RAs produced modest improvements in glycaemic control, lowering glycated haemoglobin (HbA1c) (0.56%) and increasing time-in-range (TIR), while reducing total and basal daily insulin requirements, body weight (3.6 kg) and body mass index (BMI) (1.05 kg/m2)

Many patients report fewer hunger pangs, reduced cravings, boosted energy for exercise, and improvements in blood markers like glucose and cholesterol within weeks

More recently, they have gained attention for their potential to aid weight loss

Alternatively, Oral Wegovy offers the same GLP-1 agonist treatment in a pill form, approved for those who prefer an oral regimen over an injection

The financial burden of obesity on the Canadian healthcare system exceeds $7 billion annually when accounting for direct medical costs and indirect productivity losses

This benefit persisted across subgroups and was only partially attributable to weight loss, suggesting direct cardioprotective effects beyond adiposity reduction