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Using the same protocol as in Figure 1A, we administered vehicle or liraglutide to fasted control mice and mice lacking the GLP-1R in neurons targeted by the Wnt1 - Cre2 driver (Wnt1 Glp1r/ ) or in glutamatergic neurons (Vglut2 Glp1r/ )

As obesity rates remain high in the U.S., millions of people are exploring medical weight management options

[DOI] [PMC free article] [PubMed] [Google Scholar] 12.Pratchayasakul W., Jinawong K., Pongkan W., Jaiwongkam T., Arunsak B., Chunchai T., Tokuda M., Chattipakorn N., Chattipakorn S.C

In the STEP trials, adults taking semaglutide experienced significant weight loss compared with placebo

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Diabetes Care 2011;34: 14811486