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In the largest pharmacogenomics GWAS of GLP-1 medications to date (15,237 participants, replicated in the All of Us cohort), researchers identified a missense variant in GLP1R the gene encoding the very receptor that semaglutide and tirzepatide bind that significantly predicts how much weight a person loses on treatment

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PCOD (Polycystic Ovarian Disease) and PCOS (Polycystic Ovary Syndrome) are among the most common hormonal disorders affecting women today.