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Notably, exendin 939 alleviated CAP-induced acute pain, as well as chronic pain induced by complete Freunds adjuvant (CFA) and spared nerve injury (SNI), in mice without causing hyperthermia associated with other TRPV1 inhibitors

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doi: 10.1056/NEJMoa1603827 11 MarsoSPBainSCConsoliAEliaschewitzFGJdarELeiterLAet al

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5.2 Safety evaluation In both clinical trials and real-world settings, tirzepatide has demonstrated a favorable safety and tolerability profile

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