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Metformin Metformin is a biguanide that improves glycemic control in patients with type 2 diabetes mellitus, lowering both basal and postprandial plasma glucose

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The reverse switch from tirzepatide to semaglutide is less common but occasionally necessary, usually due to insurance coverage or cost considerations

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Contact your healthcare provider if you experience: Excessive thirst with frequent urination : This combination may indicate inadequately controlled diabetes or, rarely, new-onset diabetes