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Initially approved under the name Mounjaro to treat Type 2 diabetes, many patients were prescribed tirzepatide off-label for weight loss

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By managing blood sugar levels and addressing underlying risk factors, tirzepatide may help individuals with diabetes reduce their overall cardiovascular risk and improve their heart health

Disconnect between signalling potency and in vivo efficacy of pharmacokinetically optimised biased glucagon-like peptide-1 receptor agonists
Continue the prescribed dose escalation and give each dose level at least four weeks before evaluating its effectiveness
