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Moreover, it boosts endothelial permeability by reducing the levels of Coll5a1, Lama4, and Sparc in the extracellular matrix and cytoskeleton [39]

Postdoctoral Science Foundation of China (2022M710806 to Z.C

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The mechanisms behind this have been hotly debated, with it claimed to be an indirect effect mediated through increased insulin or somatostatin secretion (98, 99), while some have indicated the effect is more direct (100), especially given the presence, albeit at low expression (~10%), of GLP-1R on alpha-cells (101)

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