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The good news: Experts say people who prefer drug-free GLP-1 alternatives have plenty of natural options that deliver all the benefits without the GI upset

In a phase I clinical trial, patients who were overweight or obese were able to reduce their body weight by 4.8% (3 mg dosage), 6.4% (4.5 mg), and 6.0% (6 mg) after receiving a once-weekly dose of mazdutide [51]
Heerspink HJL, Lu Z, Du Y, Duffin KL, Coskun T, Haupt A et al

Store Trulicity in a refrigerator

Some diabetes medications, including sulfonylureas and insulin, may interact with GLP-1 medications and increase the risk of hypoglycemia

This albumin binding dramatically extends the peptide half-life to approximately six days, which supports once-weekly subcutaneous administration
